منابع مشابه
Mucosal drug delivery.
This review focuses on epithelial drug transport mechanisms in mucosal drug delivery: the final step of a four-part process. Reference is made to the mucosae lining the oral cavity and the gastrointestinal tract, the two mucosae most often succumbing to the side effects of cytotoxic chemotherapeutic drugs. This review will be devoted to carrier-mediated transport, particularly as it relates to ...
متن کاملSystemic Drug Delivery via the Buccal Mucosal Route
is perhaps the most preferred by patients and clinicians alike. However, peroral administration of drugs has disadvantages, such as hepatic first-pass metabolism and enzymatic degradation within the gastrointestinal (GI) tract, that prohibit oral administration of certain classes of drugs, especially peptides and proteins. Consequently, other absorptive mucosa are considered as potential sites ...
متن کاملTherapeutics Applications of Nanosuspension in Topical/ Mucosal Drug Delivery
During the last two decades, many modern technologies have been established in the pharmaceutical research and development area. The automation of the drug discovery process by technologies such as high-throughput screening, combinatorial chemistry, and computer-aided drug design is leading to a vast number of drug candidates possessing a very good efficacy [1]. Unfortunately, many of these dru...
متن کاملTherapeutics Applications of Nanosuspension in Topical/ Mucosal Drug Delivery
During the last two decades, many modern technologies have been established in the pharmaceutical research and development area. The automation of the drug discovery process by technologies such as high-throughput screening, combinatorial chemistry, and computer-aided drug design is leading to a vast number of drug candidates possessing a very good efficacy [1]. Unfortunately, many of these dru...
متن کاملChitosan-based Nanoparticles in Mucosal Vaccine Delivery
Most infectious diseases are caused by pathogenic infiltrations from the mucosal tract. Nowadays, the use of vaccines has been widely investigated for the prevention of different infectious diseases, infertility, immune disorders, malignancies, and allergies. Broad-spectrum adjuvant substances have been studied for immune system stimulation with a greater efficiency against specific antigens. V...
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ژورنال
عنوان ژورنال: JNCI Monographs
سال: 2001
ISSN: 1052-6773,1745-6614
DOI: 10.1093/oxfordjournals.jncimonographs.a003439